I found this answer via google because I wanted to unpack a re.search() result with multiple groups directly into multiple variables. While this might be obvious for some, it was not for me because I always used group() in the past, so maybe it helps someone in the future who also did not know about group*s*().
s = "2020:12:30"year, month, day = re.search(r"(\d+):(\d+):(\d+)", s).groups()